Her house was originally Minnie Mouse's house after Oswald built it alongside a house for Mickey to live in when those two were forgotten. However, it turned into Ortensia's house an unknown time for unknown reasons later. After Ortensia got consumed by the Blot, her house is deserted and locked. Animatronic Goofy was the last person in her house when he cleaned it, and he left the door locked. Only if Mickey repairs Goofy will he be able to access the house. Inside are five crying Bunny Children, missing their mommy, and Ortensia's Locket, which Mickey can give to Oswald for a Health Upgrade or to Laralee for 250 E-Tickets.
In Epic Mickey 2: The Power of TwoOrtensia house reappears in Epic Mickey 2: The Power of Two. It has been somewhat damaged by the earthquakes, but not as bad as most other buildings. The "My Other House is a Castle pin" can be found in Ortensia's house and Ortensia herself will come back when the projector screens are fixed. She will give a quest to bring the Bunny Children back home (who were scattered around Wasteland thanks to the earthquakes).
- It is unknown how long the Bunny Children have been in Ortensia's house, since it's been locked for a long time.
- There's also an unlockable piece of concept art called "Ortensia's House" that can be found in a hidden alcove between the real Ortensia's house and Clarabelle's House (use thinner to reveal on the back wall).
- If Mickey uses the spin move in her house, one of the Bunny Children can be knocked around.